It doesn’t need to: if you’ve been maintaining the property to a decent standard and have installed new appliances and fittings, the house should appeal to new buyers – even though it might have had multiple tenants.
How easy the property is to sell afterwards does depend slightly on the type of rental property you own, however. In many cases, your potential buyers may be homeowners rather than landlords. A spacious house or flat will appeal to families and young professionals respectively, whether it’s been rented out or lived in by the owner. But if your Buy to Let property has been providing student accommodation on campus, for instance, it may have limited appeal to non-landlords.